Panama

David is Panama’s second-largest city and the capital of Chiriquí Province. It's more a center of agricultural industry than a cultural hub. Yet with foreign capital flowing into Chiriquí, David is rapidly gaining wealth and importance, and is poised to boom.

For most travelers, the archipelago is Bocas del Toro. Caribbean clichés aside, there’s no shortage of postcard-pretty beaches, emerald waters and swaying palms, and scads of things to see and do.

Although it’s just a 10-minute boat ride from the town of Bocas del Toro, Isla Bastimentos is like a different world. Some travelers say this is their favorite island in their favorite part of Panama. The northwest coast of the island is home to palm-fringed beaches that serve as nesting grounds for sea turtles, while most of the northern and southern coasts consist of mangrove islands and coral reefs that lie within the boundaries of the Parque Nacional Marino Isla Bastimentos.

With white sand and waving palms, the islands of the turquoise Archipiélago de San Blas of the Comarca de Guna Yala are a vision of paradise. This is home to the Guna people, the first indigenous group in Latin America to gain autonomy. Though they have had contact with Europeans since Columbus sailed these waters in 1502, traditional identity and way of life remain paramount.

Coclé is known to Panamanians as the land of salt, sugar and presidents. More salt has been reclaimed from the sea, more sugar refined and more Panamanian presidents born here than in any other province. These facts are the source of great civic pride, but Coclé offers a lot more than table condiments and political legacies.

This Caribbean fishing village is so laid-back and languorous, it's hard to imagine it was once the greatest Spanish port in Central America. Mules carried Peruvian gold and Oriental treasures to Panama City via the fortresses at Portobelo. Though English privateers destroyed them many times throughout their history, several of these atmospheric colonial fortresses still stand amid village homes.

One of the most cosmopolitan capitals in Central America, Panama City is both a vibrant metropolis and a gateway to incredible tropical escapes.

Cherished as Panama's cultural heart and soul, the Península de Azuero is a farming and ranching hub. The area's rolling hills are matched by a long and lovely coastline. Over time the peninsula has seen stark transformations – from verdant rainforest to cattle country, from indigenous land to Spanish stronghold and, finally, from a quiet town to surf central and one of Panama’s travel hot spots.

The archipelago’s most developed island is home to the provincial capital of Bocas del Toro. From the mid-1990s, foreign investors flooded the island, creating hotels, restaurants and condos while infrastructure for water, trash and sewage lagged far behind. Today the island, which runs on diesel, struggles to find a balance between satisfying development and serving community needs.

The highland rainforests are the heart of Chiriquí Province. From the rugged mountains of Parque Internacional La Amistad and the misty hills of Boquete to the continental divide traversing the cordillera (mountain range), this is probably the only spot in Panama where you might need a sweater. While Panamanians relish the chill, you’ll appreciate the astounding natural beauty throughout the region.