Panama

For most travelers, the archipelago is Bocas del Toro. Caribbean clichés aside, there’s no shortage of postcard-pretty beaches, emerald waters and swaying palms, and scads of things to see and do.

Panamá Province has a rich history of pirates, plunder and pearls. Although it's the most populous province in the country, Panamá can be as big or as small as you want it to be. Tranquil rainforests and sizzling beaches are yours to explore, and the comforts of the capital are never more than an hour away.

Although it’s just a 10-minute boat ride from the town of Bocas del Toro, Isla Bastimentos is like a different world. Some travelers say this is their favorite island in their favorite part of Panama. The northwest coast of the island is home to palm-fringed beaches that serve as nesting grounds for sea turtles, while most of the northern and southern coasts consist of mangrove islands and coral reefs that lie within the boundaries of the Parque Nacional Marino Isla Bastimentos.

One of the world’s richest biomes is the 2240-sq-mile (5790-sq-km) Parque Nacional Darién, where the primeval meets the present with scenery nearly unaltered from one million years ago. Even today in the Darién, the Emberá and Wounaan people maintain many of their traditional practices and retain generations-old knowledge of the rainforest. 

Colón Province is much, much more than its run-down capital. Think pristine beaches and lowland rainforests, colonial splendor and the modern engineering marvel of the Panama Canal. Portobelo, with its growing music and art scene, shows the best of the rich culture of the Congos, descendants of enslaved Africans who have preserved the legacy of their ancestors, while the train trip between Panama City and Colón remains one of the greatest rail journeys in the Americas.

Boquete is known for its cool, fresh climate and pristine natural surroundings. Flowers, coffee, vegetables and citrus fruits flourish in its rich soil, and the friendliness of the locals seems to rub off on everyone who passes through. Boquete gained a deluge of expats after the American Association for Retired Persons (AARP) named it a top retirement spot. Until you see the gated communities and sprawling estates dotting the hillsides up close, though, you'd be hard-pressed to see what the fuss is about.

This Caribbean fishing village is so laid-back and languorous, it's hard to imagine it was once the greatest Spanish port in Central America. Mules carried Peruvian gold and Oriental treasures to Panama City via the fortresses at Portobelo. Though English privateers destroyed them many times throughout their history, several of these atmospheric colonial fortresses still stand amid village homes.

The name of Veraguas province (literally “see waters”) is both descriptive and accurate – it is the only one of Panama's provinces and comarcas (indigenous districts) to border both the Pacific Ocean and the Caribbean Sea.

Colorful and full of Caribbean-style clapboard houses, Bocas del Toro (better known simply as Bocas town) was built by the United Fruit Company in the early 20th century. Today it is a relaxed community of West Indians, Latinos and resident gringos, with a friendly atmosphere that is contagious. It’s an easy place to adapt to and even easier to linger in.

Officially known as El Valle de Antón, this picturesque town is nestled in the crater of a huge extinct volcano, and ringed by verdant forests and jagged peaks. El Valle is a popular weekend getaway for urban dwellers in need of fresh air and scenery and is also a retirement community for foreigners, with some 200 resident expats from more than 40 countries. With an extensive network of trails, this is a superb place for walking, hiking or horseback riding. Nearby forests offer excellent birdwatching, and the valleys of El Valle are home to an impressive set of waterfalls and natural pools.