Panama

One of the world’s richest biomes is the 2240-sq-mile (5790-sq-km) Parque Nacional Darién, where the primeval meets the present with scenery nearly unaltered from one million years ago. Even today in the Darién, the Emberá and Wounaan people maintain many of their traditional practices and retain generations-old knowledge of the rainforest. 

Colón Province is much, much more than its run-down capital. Think pristine beaches and lowland rainforests, colonial splendor and the modern engineering marvel of the Panama Canal. Portobelo, with its growing music and art scene, shows the best of the rich culture of the Congos, descendants of enslaved Africans who have preserved the legacy of their ancestors, while the train trip between Panama City and Colón remains one of the greatest rail journeys in the Americas.

With white sand and waving palms, the islands of the turquoise Archipiélago de San Blas of the Comarca de Guna Yala are a vision of paradise. This is home to the Guna people, the first indigenous group in Latin America to gain autonomy. Though they have had contact with Europeans since Columbus sailed these waters in 1502, traditional identity and way of life remain paramount.

One of the most cosmopolitan capitals in Central America, Panama City is both a vibrant metropolis and a gateway to incredible tropical escapes.

For most travelers, the archipelago is Bocas del Toro. Caribbean clichés aside, there’s no shortage of postcard-pretty beaches, emerald waters and swaying palms, and scads of things to see and do.

Officially known as El Valle de Antón, this picturesque town is nestled in the crater of a huge extinct volcano, and ringed by verdant forests and jagged peaks. El Valle is a popular weekend getaway for urban dwellers in need of fresh air and scenery and is also a retirement community for foreigners, with some 200 resident expats from more than 40 countries. With an extensive network of trails, this is a superb place for walking, hiking or horseback riding. Nearby forests offer excellent birdwatching, and the valleys of El Valle are home to an impressive set of waterfalls and natural pools.

David is Panama’s second-largest city and the capital of Chiriquí Province. It's more a center of agricultural industry than a cultural hub. Yet with foreign capital flowing into Chiriquí, David is rapidly gaining wealth and importance, and is poised to boom.

Colorful and full of Caribbean-style clapboard houses, Bocas del Toro (better known simply as Bocas town) was built by the United Fruit Company in the early 20th century. Today it is a relaxed community of West Indians, Latinos and resident gringos, with a friendly atmosphere that is contagious. It’s an easy place to adapt to and even easier to linger in.

The archipelago’s most developed island is home to the provincial capital of Bocas del Toro. From the mid-1990s, foreign investors flooded the island, creating hotels, restaurants and condos while infrastructure for water, trash and sewage lagged far behind. Today the island, which runs on diesel, struggles to find a balance between satisfying development and serving community needs.

This Caribbean fishing village is so laid-back and languorous, it's hard to imagine it was once the greatest Spanish port in Central America. Mules carried Peruvian gold and Oriental treasures to Panama City via the fortresses at Portobelo. Though English privateers destroyed them many times throughout their history, several of these atmospheric colonial fortresses still stand amid village homes.