Panama

One of the most cosmopolitan capitals in Central America, Panama City is both a vibrant metropolis and a gateway to incredible tropical escapes.

The name of Veraguas province (literally “see waters”) is both descriptive and accurate – it is the only one of Panama's provinces and comarcas (indigenous districts) to border both the Pacific Ocean and the Caribbean Sea.

One of the world’s richest biomes is the 2240-sq-mile (5790-sq-km) Parque Nacional Darién, where the primeval meets the present with scenery nearly unaltered from one million years ago. Even today in the Darién, the Emberá and Wounaan people maintain many of their traditional practices and retain generations-old knowledge of the rainforest. 

Boquete is known for its cool, fresh climate and pristine natural surroundings. Flowers, coffee, vegetables and citrus fruits flourish in its rich soil, and the friendliness of the locals seems to rub off on everyone who passes through. Boquete gained a deluge of expats after the American Association for Retired Persons (AARP) named it a top retirement spot. Until you see the gated communities and sprawling estates dotting the hillsides up close, though, you'd be hard-pressed to see what the fuss is about.

David is Panama’s second-largest city and the capital of Chiriquí Province. It's more a center of agricultural industry than a cultural hub. Yet with foreign capital flowing into Chiriquí, David is rapidly gaining wealth and importance, and is poised to boom.

Cherished as Panama's cultural heart and soul, the Península de Azuero is a farming and ranching hub. The area's rolling hills are matched by a long and lovely coastline. Over time the peninsula has seen stark transformations – from verdant rainforest to cattle country, from indigenous land to Spanish stronghold and, finally, from a quiet town to surf central and one of Panama’s travel hot spots.

Coclé is known to Panamanians as the land of salt, sugar and presidents. More salt has been reclaimed from the sea, more sugar refined and more Panamanian presidents born here than in any other province. These facts are the source of great civic pride, but Coclé offers a lot more than table condiments and political legacies.

Although it’s just a 10-minute boat ride from the town of Bocas del Toro, Isla Bastimentos is like a different world. Some travelers say this is their favorite island in their favorite part of Panama. The northwest coast of the island is home to palm-fringed beaches that serve as nesting grounds for sea turtles, while most of the northern and southern coasts consist of mangrove islands and coral reefs that lie within the boundaries of the Parque Nacional Marino Isla Bastimentos.

This Caribbean fishing village is so laid-back and languorous, it's hard to imagine it was once the greatest Spanish port in Central America. Mules carried Peruvian gold and Oriental treasures to Panama City via the fortresses at Portobelo. Though English privateers destroyed them many times throughout their history, several of these atmospheric colonial fortresses still stand amid village homes.

Among Central America's top surf spots, Santa Catalina is still somewhat remote with limited development and home to some seriously wicked surf. Life here is pretty tranquil, in a fishing village where skateboards rip down main street and kids go barefoot but clothing is required to walk to and from the beach. Most non-surfers discover the area as the main springboard for day and overnight trips to Isla de Coiba and its national park, where there's outstanding scuba diving and snorkeling.