Panama

With white sand and waving palms, the islands of the turquoise Archipiélago de San Blas of the Comarca de Guna Yala are a vision of paradise. This is home to the Guna people, the first indigenous group in Latin America to gain autonomy. Though they have had contact with Europeans since Columbus sailed these waters in 1502, traditional identity and way of life remain paramount.

This Caribbean fishing village is so laid-back and languorous, it's hard to imagine it was once the greatest Spanish port in Central America. Mules carried Peruvian gold and Oriental treasures to Panama City via the fortresses at Portobelo. Though English privateers destroyed them many times throughout their history, several of these atmospheric colonial fortresses still stand amid village homes.

Boquete is known for its cool, fresh climate and pristine natural surroundings. Flowers, coffee, vegetables and citrus fruits flourish in its rich soil, and the friendliness of the locals seems to rub off on everyone who passes through. Boquete gained a deluge of expats after the American Association for Retired Persons (AARP) named it a top retirement spot. Until you see the gated communities and sprawling estates dotting the hillsides up close, though, you'd be hard-pressed to see what the fuss is about.

Panamá Province has a rich history of pirates, plunder and pearls. Although it's the most populous province in the country, Panamá can be as big or as small as you want it to be. Tranquil rainforests and sizzling beaches are yours to explore, and the comforts of the capital are never more than an hour away.

For most travelers, the archipelago is Bocas del Toro. Caribbean clichés aside, there’s no shortage of postcard-pretty beaches, emerald waters and swaying palms, and scads of things to see and do.

The name of Veraguas province (literally “see waters”) is both descriptive and accurate – it is the only one of Panama's provinces and comarcas (indigenous districts) to border both the Pacific Ocean and the Caribbean Sea.

With its Caribbean islands dotting a shock of blue waters, Bocas del Toro is all that's tropical. This is Panama’s principal tourist draw and it will no doubt provide some of your most memorable experiences. The archipelago consists of six densely forested islands, scores of uninhabited islets and the Parque Nacional Marino Isla Bastimentos, Panama’s oldest marine park.

Colón Province is much, much more than its run-down capital. Think pristine beaches and lowland rainforests, colonial splendor and the modern engineering marvel of the Panama Canal. Portobelo, with its growing music and art scene, shows the best of the rich culture of the Congos, descendants of enslaved Africans who have preserved the legacy of their ancestors, while the train trip between Panama City and Colón remains one of the greatest rail journeys in the Americas.

The archipelago’s most developed island is home to the provincial capital of Bocas del Toro. From the mid-1990s, foreign investors flooded the island, creating hotels, restaurants and condos while infrastructure for water, trash and sewage lagged far behind. Today the island, which runs on diesel, struggles to find a balance between satisfying development and serving community needs.

Although it’s just a 10-minute boat ride from the town of Bocas del Toro, Isla Bastimentos is like a different world. Some travelers say this is their favorite island in their favorite part of Panama. The northwest coast of the island is home to palm-fringed beaches that serve as nesting grounds for sea turtles, while most of the northern and southern coasts consist of mangrove islands and coral reefs that lie within the boundaries of the Parque Nacional Marino Isla Bastimentos.