Quiché is the homeland of the K'iche' people, though other groups form the fabric of this culturally diverse region, most notably the Ixil of the eastern Cuchumatanes mountains. Most visitors who come to this largely forgotten pocket of the country are on a jaunt to the famous market at Chichicastenango. Similarly captivating commerce is conducted in the less trammeled territory of Santa Cruz del Quiché, the departmental capital to the north. On its outskirts lie the mysterious ruins of K'umarcaaj, the last capital city of the K'iche'. Adventurous souls push further north for Nebaj, heart of the culturally vibrant Ixil Triangle, with myriad hiking opportunities.
Spreading onto a peninsula at the base of the volcano of the same name, San Pedro remains among the most visited of the lakeside villages – due as much to its reasonably priced accommodations and global social scene as to its spectacular setting. It's a backpacker haven – travelers tend to dig in here for a spell, in pursuit of (in no particular order) drinking, fire-twirling, African drumming, Spanish classes, volcano hiking, hot-tub soaking, partying and hammock swinging.
The coastal area around Monterrico is a totally different Guatemala. Life here is steeped with a sultry, tropical flavor, with rustic wooden-slat and thatched-roof architecture and awesome volcanoes that shimmer in the hinterland. It's fast becoming popular with foreigners as a beach break from Antigua or Guatemala City. On weekdays it's relatively quiet, but on weekends and holidays it teems with Guatemalan families.
This region is an interesting mix of local villages, often with little Spanish spoken in favor of Indigenous languages, larger cities and some truly top-notch tourist attractions. It can be beastly hot at times, particularly just before the rainy season from February to May. Oddly, this is when some of the sights are best visited, as they are most known for swimming, spelunking, or getting wet and muddy.
Surrounded by valleys with mountains serrating the horizons, Chichicastenango can seem a world away from the rest of Guatemala. When its narrow cobbled streets and red-tiled roofs are enveloped in mist, it's downright magical. The crowds of crafts vendors and tour groups who flock in for the huge Thursday and Sunday markets lend it a lively commercial atmosphere. Masheños (citizens of Chichicastenango) adhere strongly to Indigenous religions and ceremonies, and the town's various cofradías (religious brotherhoods) hold processions in observance of their saints around the church of Santo Tomás.
The highlands – El Altiplano – stretch from Antigua to the Mexican border; they comprise Guatemala's most breathtaking region by some degree. Maya identity is stronger here than anywhere in the country and over a dozen distinct groups dwell within the region, each with its own language and clothing. Indigenous tradition blends most tantalizingly with Spanish, and it is common to see Maya rituals taking place in front of and inside colonial churches.
With its pastel houses cascading down from a central plaza to the emerald waters of Lago de Petén Itzá, the island town of Flores evokes Venice or somewhere Mediterranean. A 0.3-mile (500m) causeway connects Flores to its humbler sister town of Santa Elena on the mainland, which then merges into the community of San Benito to the west. The three towns actually form one large settlement, often referred to simply as Flores.
Lago de Atitlán leaves even the most seasoned travelers marveling. Fishers ply the lake's aquamarine surface. Fertile hills dot the landscape, and over everything looms the volcanoes, permeating the entire area with unique and striking beauty. It never looks the same twice. No wonder many have fallen in love with the place and made their homes here.
San Juan La Laguna is just 1.2 miles (2km) west by road from busy San Pedro, on a rise above a spectacular bay, but this neat, mellow village has escaped many of the excesses of its neighbor, and some travelers find it a more tranquil setting in which to study Spanish or experience local life. San Juan is special: the Tz'utujil inhabitants take pride in their craft traditions – particularly painting and weaving – and have developed their own tourism infrastructure to highlight their culture to outsiders.
Antigua's beguiling beauty starts to seduce the moment you arrive. Once capital of Guatemala, its streetscapes of pastel facades unfold beneath the gaze of three volcanoes, and meticulously restored colonial buildings sit next to picturesque ruins in park-like surroundings. The city's World Heritage–listed status means that even fast-food chains have to hide themselves behind traditional building facades.