Stretching from the steamy lowland forests of El Petén to the dry tropics of the Río Motagua valley, and from the edge of the Western Highlands to the Caribbean Sea, this is Guatemala's most diverse region.
San Juan La Laguna is just 1.2 miles (2km) west by road from busy San Pedro, on a rise above a spectacular bay, but this neat, mellow village has escaped many of the excesses of its neighbor, and some travelers find it a more tranquil setting in which to study Spanish or experience local life. San Juan is special: the Tz'utujil inhabitants take pride in their craft traditions – particularly painting and weaving – and have developed their own tourism infrastructure to highlight their culture to outsiders.
Quiché is the homeland of the K'iche' people, though other groups form the fabric of this culturally diverse region, most notably the Ixil of the eastern Cuchumatanes mountains. Most visitors who come to this largely forgotten pocket of the country are on a jaunt to the famous market at Chichicastenango. Similarly captivating commerce is conducted in the less trammeled territory of Santa Cruz del Quiché, the departmental capital to the north. On its outskirts lie the mysterious ruins of K'umarcaaj, the last capital city of the K'iche'. Adventurous souls push further north for Nebaj, heart of the culturally vibrant Ixil Triangle, with myriad hiking opportunities.
The highlands – El Altiplano – stretch from Antigua to the Mexican border; they comprise Guatemala's most breathtaking region by some degree. Maya identity is stronger here than anywhere in the country and over a dozen distinct groups dwell within the region, each with its own language and clothing. Indigenous tradition blends most tantalizingly with Spanish, and it is common to see Maya rituals taking place in front of and inside colonial churches.
Spreading onto a peninsula at the base of the volcano of the same name, San Pedro remains among the most visited of the lakeside villages – due as much to its reasonably priced accommodations and global social scene as to its spectacular setting. It's a backpacker haven – travelers tend to dig in here for a spell, in pursuit of (in no particular order) drinking, fire-twirling, African drumming, Spanish classes, volcano hiking, hot-tub soaking, partying and hammock swinging.
Lívingston is unlike anywhere else in Guatemala. Its Garifuna people, their colors, culture, rhythms, flavors, and disposition, are the best reason to visit – nowhere else in Guatemala will you find such a fun and relaxed vibe. But it's not just the people: good beaches are nearby and the slow-and-easy take on life is enchanting. Here boats lie derelict in picturesque decay; people paddleboard or kayak lazily amid refreshing ocean breezes; and pelicans soar overhead as happy hour starts in late afternoon. It's just lovely.
Vast, sparsely populated and jungle-covered, Guatemala's largest and northernmost department is a wonderland of exploration. Whether it's the spectacular architectural achievements of the Classic Maya, the bounty of the forest or the chance to lounge lakeside that inspires you, it's all here in abundance.
The coastal area around Monterrico is a totally different Guatemala. Life here is steeped with a sultry, tropical flavor, with rustic wooden-slat and thatched-roof architecture and awesome volcanoes that shimmer in the hinterland. It's fast becoming popular with foreigners as a beach break from Antigua or Guatemala City. On weekdays it's relatively quiet, but on weekends and holidays it teems with Guatemalan families.
The busiest and most built-up lakeside town, Panajachel ('Pana') is the gateway to Lago de Atitlán for most travelers. Strolling the main street, Calle Santander – crammed with travel agencies, handicraft hawkers and rowdy bars, dodging tuk-tuks all the way – you may be forgiven for supposing this paradise lost.
Santiago Atitlán is the largest of the lake communities, with a strong indigenous identity. Many atitecos (as its people are known) proudly adhere to a traditional Tz'utujil Maya lifestyle. Women wear purple-striped skirts and huipiles embroidered with colored birds and flowers, while older men still wear lavender or maroon striped embroidered pants. The town's cofradías (brotherhoods) maintain the syncretic traditions and rituals of Maya Catholicism. There's a large arts and crafts scene here too. Boatbuilding is a local industry, and rows of rough-hewn cayucos (dugout canoes) are lined up along the shore. The liveliest days to visit are Friday and Sunday, the main market days, but any day will do.