Quiché is the homeland of the K'iche' people, though other groups form the fabric of this culturally diverse region, most notably the Ixil of the eastern Cuchumatanes mountains. Most visitors who come to this largely forgotten pocket of the country are on a jaunt to the famous market at Chichicastenango. Similarly captivating commerce is conducted in the less trammeled territory of Santa Cruz del Quiché, the departmental capital to the north. On its outskirts lie the mysterious ruins of K'umarcaaj, the last capital city of the K'iche'. Adventurous souls push further north for Nebaj, heart of the culturally vibrant Ixil Triangle, with myriad hiking opportunities.
Lívingston is unlike anywhere else in Guatemala. Its Garifuna people, their colors, culture, rhythms, flavors, and disposition, are the best reason to visit – nowhere else in Guatemala will you find such a fun and relaxed vibe. But it's not just the people: good beaches are nearby and the slow-and-easy take on life is enchanting. Here boats lie derelict in picturesque decay; people paddleboard or kayak lazily amid refreshing ocean breezes; and pelicans soar overhead as happy hour starts in late afternoon. It's just lovely.
The highlands – El Altiplano – stretch from Antigua to the Mexican border; they comprise Guatemala's most breathtaking region by some degree. Maya identity is stronger here than anywhere in the country and over a dozen distinct groups dwell within the region, each with its own language and clothing. Indigenous tradition blends most tantalizingly with Spanish, and it is common to see Maya rituals taking place in front of and inside colonial churches.
The mountainous departments of Quetzaltenango, Totonicapán and Huehuetenango are generally less visited by tourists than regions closer to Guatemala City. But with extraordinarily dramatic scenery and vibrant indigenous culture, this part of the country presents an invariably fascinating panorama. Highlights of any visit include Quetzaltenango ('Xela' for short), Guatemala's second-largest city, with an ever-growing language school and volunteer work scene; the nearby town of Zunil, with its volcanically heated springs and Maya deity; ascents of the volcanoes around Quetzaltenango; and the remote mountain enclave of Todos Santos Cuchumatán, north of Huehuetenango, with a strong traditional culture and excellent walking possibilities.
Quetzaltenango is Guatemala's second city. It has a great atmosphere – not too big, not too small, enough foreigners to support a good range of hotels and restaurants, but not so many that it loses its national flavor. The city center has an interesting mix of architectural styles – once the Spanish moved out, the Germans moved in and their architecture gives the zone a somber, even Gothic, feel.
Depending on who you talk to, Guatemala City (or Guate as it's also known) is either big, dirty, dangerous and utterly forgettable, or big, dirty, dangerous and utterly fascinating. Either way, there's no doubt there's an energy here unlike anywhere else in Guatemala. It's a place where dilapidated buses belch fumes next to BMWs and Hummers, and where skyscrapers drop shadows on shantytowns.
Stretching from the steamy lowland forests of El Petén to the dry tropics of the Río Motagua valley, and from the edge of the Western Highlands to the Caribbean Sea, this is Guatemala's most diverse region.
San Juan La Laguna is just 1.2 miles (2km) west by road from busy San Pedro, on a rise above a spectacular bay, but this neat, mellow village has escaped many of the excesses of its neighbor, and some travelers find it a more tranquil setting in which to study Spanish or experience local life. San Juan is special: the Tz'utujil inhabitants take pride in their craft traditions – particularly painting and weaving – and have developed their own tourism infrastructure to highlight their culture to outsiders.
This is a very different Guatemala – a lush and sultry landscape dotted with palm trees and inhabited by international sailors (around the yachtie haven of Río Dulce and the working port of Puerto Barrios) and one of the country's lesser-known ethnic groups, the Garifuna (around Lívingston).
Santa Cruz fits the typically dual nature of the Atitlán villages, comprising both a waterfront resort (home of the lake's scuba-diving outfit) and an indigenous Kaqchiquel village. The village is about 0.35 miles (600m) uphill from the dock (there are tuk-tuks if you don't fancy the stiff walk). It's a lovely spot, with relaxing accommodations, activities on the water and a complete lack of hustle.