Guatemala

The busiest and most built-up lakeside town, Panajachel ('Pana') is the gateway to Lago de Atitlán for most travelers. Strolling the main street, Calle Santander – crammed with travel agencies, handicraft hawkers and rowdy bars, dodging tuk-tuks all the way – you may be forgiven for supposing this paradise lost.

Santiago Atitlán is the largest of the lake communities, with a strong indigenous identity. Many atitecos (as its people are known) proudly adhere to a traditional Tz'utujil Maya lifestyle. Women wear purple-striped skirts and huipiles embroidered with colored birds and flowers, while older men still wear lavender or maroon striped embroidered pants. The town's cofradías (brotherhoods) maintain the syncretic traditions and rituals of Maya Catholicism. There's a large arts and crafts scene here too. Boatbuilding is a local industry, and rows of rough-hewn cayucos (dugout canoes) are lined up along the shore. The liveliest days to visit are Friday and Sunday, the main market days, but any day will do.

Separated from the highlands by a chain of volcanoes, the flatlands that run down to the Pacific are universally known as La Costa. It's a sultry region – hot and wet or hot and dry, depending on the time of year – with rich volcanic soil good for growing coffee, palm-oil seeds and sugarcane.

Antigua's beguiling beauty starts to seduce the moment you arrive. Once capital of Guatemala, its streetscapes of pastel facades unfold beneath the gaze of three volcanoes, and meticulously restored colonial buildings sit next to picturesque ruins in park-like surroundings. The city's World Heritage–listed status means that even fast-food chains have to hide themselves behind traditional building facades.

Quetzaltenango is Guatemala's second city. It has a great atmosphere – not too big, not too small, enough foreigners to support a good range of hotels and restaurants, but not so many that it loses its national flavor. The city center has an interesting mix of architectural styles – once the Spanish moved out, the Germans moved in and their architecture gives the zone a somber, even Gothic, feel.

San Juan La Laguna is just 1.2 miles (2km) west by road from busy San Pedro, on a rise above a spectacular bay, but this neat, mellow village has escaped many of the excesses of its neighbor, and some travelers find it a more tranquil setting in which to study Spanish or experience local life. San Juan is special: the Tz'utujil inhabitants take pride in their craft traditions – particularly painting and weaving – and have developed their own tourism infrastructure to highlight their culture to outsiders.

Stretching from the steamy lowland forests of El Petén to the dry tropics of the Río Motagua valley, and from the edge of the Western Highlands to the Caribbean Sea, this is Guatemala's most diverse region.

One of the prettiest of the lakeside villages, San Marcos La Laguna lives a double life. The mostly Maya community occupies the higher ground, while expats and visitors cover a flat jungly patch toward the shoreline with paths snaking through banana, coffee and avocado trees. The two converge under the spreading matapalo (strangler fig) tree of the central plaza.

Quiché is the homeland of the K'iche' people, though other groups form the fabric of this culturally diverse region, most notably the Ixil of the eastern Cuchumatanes mountains. Most visitors who come to this largely forgotten pocket of the country are on a jaunt to the famous market at Chichicastenango. Similarly captivating commerce is conducted in the less trammeled territory of Santa Cruz del Quiché, the departmental capital to the north. On its outskirts lie the mysterious ruins of K'umarcaaj, the last capital city of the K'iche'. Adventurous souls push further north for Nebaj, heart of the culturally vibrant Ixil Triangle, with myriad hiking opportunities.

This region is an interesting mix of local villages, often with little Spanish spoken in favor of Indigenous languages, larger cities and some truly top-notch tourist attractions. It can be beastly hot at times, particularly just before the rainy season from February to May. Oddly, this is when some of the sights are best visited, as they are most known for swimming, spelunking, or getting wet and muddy.