Guatemala

Depending on who you talk to, Guatemala City (or Guate as it's also known) is either big, dirty, dangerous and utterly forgettable, or big, dirty, dangerous and utterly fascinating. Either way, there's no doubt there's an energy here unlike anywhere else in Guatemala. It's a place where dilapidated buses belch fumes next to BMWs and Hummers, and where skyscrapers drop shadows on shantytowns.

Spreading onto a peninsula at the base of the volcano of the same name, San Pedro remains among the most visited of the lakeside villages – due as much to its reasonably priced accommodations and global social scene as to its spectacular setting. It's a backpacker haven – travelers tend to dig in here for a spell, in pursuit of (in no particular order) drinking, fire-twirling, African drumming, Spanish classes, volcano hiking, hot-tub soaking, partying and hammock swinging.

Surrounded by valleys with mountains serrating the horizons, Chichicastenango can seem a world away from the rest of Guatemala. When its narrow cobbled streets and red-tiled roofs are enveloped in mist, it's downright magical. The crowds of crafts vendors and tour groups who flock in for the huge Thursday and Sunday markets lend it a lively commercial atmosphere. Masheños (citizens of Chichicastenango) adhere strongly to Indigenous religions and ceremonies, and the town's various cofradías (religious brotherhoods) hold processions in observance of their saints around the church of Santo Tomás.

Antigua's beguiling beauty starts to seduce the moment you arrive. Once capital of Guatemala, its streetscapes of pastel facades unfold beneath the gaze of three volcanoes, and meticulously restored colonial buildings sit next to picturesque ruins in park-like surroundings. The city's World Heritage–listed status means that even fast-food chains have to hide themselves behind traditional building facades.

Santa Cruz fits the typically dual nature of the Atitlán villages, comprising both a waterfront resort (home of the lake's scuba-diving outfit) and an indigenous Kaqchiquel village. The village is about 0.35 miles (600m) uphill from the dock (there are tuk-tuks if you don't fancy the stiff walk). It's a lovely spot, with relaxing accommodations, activities on the water and a complete lack of hustle.

The busiest and most built-up lakeside town, Panajachel ('Pana') is the gateway to Lago de Atitlán for most travelers. Strolling the main street, Calle Santander – crammed with travel agencies, handicraft hawkers and rowdy bars, dodging tuk-tuks all the way – you may be forgiven for supposing this paradise lost.

Separated from the highlands by a chain of volcanoes, the flatlands that run down to the Pacific are universally known as La Costa. It's a sultry region – hot and wet or hot and dry, depending on the time of year – with rich volcanic soil good for growing coffee, palm-oil seeds and sugarcane.

Once a spot that tourists passed through, Cobán has become a destination in its own right and one of the best in the area (outside Guatemala City) for decent food, a range of hotels and activities. For tourists it remains a great hub for taking in the surrounding natural wonders – such as Semuc Champey – in a series of day trips.

The mountainous departments of Quetzaltenango, Totonicapán and Huehuetenango are generally less visited by tourists than regions closer to Guatemala City. But with extraordinarily dramatic scenery and vibrant indigenous culture, this part of the country presents an invariably fascinating panorama. Highlights of any visit include Quetzaltenango ('Xela' for short), Guatemala's second-largest city, with an ever-growing language school and volunteer work scene; the nearby town of Zunil, with its volcanically heated springs and Maya deity; ascents of the volcanoes around Quetzaltenango; and the remote mountain enclave of Todos Santos Cuchumatán, north of Huehuetenango, with a strong traditional culture and excellent walking possibilities.

Quetzaltenango is Guatemala's second city. It has a great atmosphere – not too big, not too small, enough foreigners to support a good range of hotels and restaurants, but not so many that it loses its national flavor. The city center has an interesting mix of architectural styles – once the Spanish moved out, the Germans moved in and their architecture gives the zone a somber, even Gothic, feel.