With its pastel houses cascading down from a central plaza to the emerald waters of Lago de Petén Itzá, the island town of Flores evokes Venice or somewhere Mediterranean. A 0.3-mile (500m) causeway connects Flores to its humbler sister town of Santa Elena on the mainland, which then merges into the community of San Benito to the west. The three towns actually form one large settlement, often referred to simply as Flores.
Lago de Atitlán leaves even the most seasoned travelers marveling. Fishers ply the lake's aquamarine surface. Fertile hills dot the landscape, and over everything looms the volcanoes, permeating the entire area with unique and striking beauty. It never looks the same twice. No wonder many have fallen in love with the place and made their homes here.
The busiest and most built-up lakeside town, Panajachel ('Pana') is the gateway to Lago de Atitlán for most travelers. Strolling the main street, Calle Santander – crammed with travel agencies, handicraft hawkers and rowdy bars, dodging tuk-tuks all the way – you may be forgiven for supposing this paradise lost.
Antigua's beguiling beauty starts to seduce the moment you arrive. Once capital of Guatemala, its streetscapes of pastel facades unfold beneath the gaze of three volcanoes, and meticulously restored colonial buildings sit next to picturesque ruins in park-like surroundings. The city's World Heritage–listed status means that even fast-food chains have to hide themselves behind traditional building facades.
Spreading onto a peninsula at the base of the volcano of the same name, San Pedro remains among the most visited of the lakeside villages – due as much to its reasonably priced accommodations and global social scene as to its spectacular setting. It's a backpacker haven – travelers tend to dig in here for a spell, in pursuit of (in no particular order) drinking, fire-twirling, African drumming, Spanish classes, volcano hiking, hot-tub soaking, partying and hammock swinging.
Stretching from the steamy lowland forests of El Petén to the dry tropics of the Río Motagua valley, and from the edge of the Western Highlands to the Caribbean Sea, this is Guatemala's most diverse region.
The coastal area around Monterrico is a totally different Guatemala. Life here is steeped with a sultry, tropical flavor, with rustic wooden-slat and thatched-roof architecture and awesome volcanoes that shimmer in the hinterland. It's fast becoming popular with foreigners as a beach break from Antigua or Guatemala City. On weekdays it's relatively quiet, but on weekends and holidays it teems with Guatemalan families.
Separated from the highlands by a chain of volcanoes, the flatlands that run down to the Pacific are universally known as La Costa. It's a sultry region – hot and wet or hot and dry, depending on the time of year – with rich volcanic soil good for growing coffee, palm-oil seeds and sugarcane.
The highlands – El Altiplano – stretch from Antigua to the Mexican border; they comprise Guatemala's most breathtaking region by some degree. Maya identity is stronger here than anywhere in the country and over a dozen distinct groups dwell within the region, each with its own language and clothing. Indigenous tradition blends most tantalizingly with Spanish, and it is common to see Maya rituals taking place in front of and inside colonial churches.
This region is an interesting mix of local villages, often with little Spanish spoken in favor of Indigenous languages, larger cities and some truly top-notch tourist attractions. It can be beastly hot at times, particularly just before the rainy season from February to May. Oddly, this is when some of the sights are best visited, as they are most known for swimming, spelunking, or getting wet and muddy.