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Draped along the banks of the Hau Giang River (Bassac River), Chau Doc sees plenty of travelers washing through on the river route between Cambodia and Vietnam. A likeable little town with significant Chinese, Cham and Khmer communities, Chau Doc's cultural diversity – apparent in the mosques, temples, churches and nearby pilgrimage sites – makes it fascinating to explore even if you're not Cambodia-bound. Taking a boat trip to the Cham communities across the river or heading to nearby Sam Mountain and Tra Su Bird Sanctuary are other highlights, while the bustling market and intriguing waterfront provide fine backdrops to a few days of relaxation.

Northwest Vietnam, with its rocky, cone-like mountains, high vistas and deep valleys, encompasses some of the most extreme geography in the country – if not all of Southeast Asia. Travelling to the more remote parts of the region takes time and effort, but those short on either can stick around Sapa, the surrounding hills of which are a microcosm of the region as a whole.

Steadily being transformed into a vast new city, Tuy Hoa is characterised by its vast plaza and multi-laned boulevards. It’s a possible overnight stop to break up a longer journey, especially for cyclists brave enough to tackle Hwy 1, but most visitors are just passing through.

Dong Van is the Ha Giang region's most popular overnight stop and, not coincidentally, is home to some solid accommodation and food. But the real reason to come is for the Sunday market, one of the region's biggest and most colourful. The town is also a good base for day treks around nearby minority villages and nearby sights such as the Lung Cu flag tower and the Lung Cam Cultural Tourist Village.

The picturesque little province of Ben Tre was always one ferry beyond the tourist traffic of My Tho and consequently developed at a more languid pace, although new bridges connecting Ben Tre with My Tho and Tra Vinh funnelled more visitors into the area. The town’s sleepy waterfront, lined with ageing villas, is easy to explore on foot, as is the rustic settlement across the bridge to the south of the centre. This is also a good place to arrange boat trips in the area, particularly for those wanting to escape the tour-bus bustle. Plus, the riverside promenade and the narrow lanes on both sides of the river are ideal for two-wheeled exploration.

Plonked about midway between My Tho and Can Tho, Vinh Long is a major transit hub and the capital of the province. For travelers, it's a gateway to island life, Cai Be floating market, abundant orchards and rural homestays.

Ho Chi Minh City (HCMC) is Vietnam at its most dizzying: a high-octane city of commerce and culture that has driven the country forward with its pulsating energy. A chaotic whirl, the city breathes life and vitality into all who settle here, and visitors cannot help but be hauled along for the ride.

Practically obliterated during the American War, Vinh was rebuilt with East German aid – hence the brutalist concrete architecture dominating downtown. The only reasons to stop here are if you're a Ho Chi Minh devotee (he was born in a nearby village), or if you're heading to Laos.

A large, prosperous coastal city, Quy Nhon (pronounced ‘hwee ngon’) boasts a terrific beach-blessed shoreline and grand boulevards. Its seaside appeal and tidy, litter-free streets make it the kind of place that affluent Vietnamese couples choose to retire to, spending their final days ocean-gazing and promenade-walking.

South of Hanoi, Ninh Binh province is blessed with natural beauty, cultural sights and the Cuc Phuong National Park. Highlights include boat trips amid karst landscapes at Tam Coc and the Unesco World Heritage-listed Trang An Grottoes.