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A popular weekend escape from HCMC, Vung Tau rocks at weekends when beach-starved locals and expats descend in numbers, but it is relatively quiet during the week. The city enjoys a spectacular location on a peninsula, with ocean on three sides; the light and sea air make it a refreshing break from sultry Saigon.

Ha Tien may be part of the Mekong Delta, but lying on the Gulf of Thailand it feels a world away from the rice fields and rivers that typify the region. There are dramatic limestone formations peppering the area, which are home to a network of caves, some of which have been turned into temples. Plantations of pepper trees cling to the hillsides. On a clear day, Phu Quoc Island is easily visible to the west.

Heading east of Hoi An, new housing and hotels mix with older rice paddies, and the riverbank meanders for around 5km to sandy beaches. This palm-fringed coastline extends north to Danang, and despite the development, there are still a few quieter stretches; it's a good area to explore independently on two wheels.

The epicentre of the Mekong Delta, Can Tho is the largest city in the region and feels like a metropolis after a few days exploring the backwaters. As the political, economic, cultural and transportation centre of the Mekong Delta, it’s a buzzing town with a lively waterfront lined with sculpted gardens, an appealing blend of narrow backstreets and wide boulevards, and perhaps the greatest concentration of foreigners in the delta. It is also the perfect base for nearby floating markets, the major draw for tourists who come here to boat along the many canals and rivers leading out of town.

The bustling port city of Phan Thiet is traditionally known for its nuoc mam (fish sauce), producing millions of liters of the stuff per annum. There's not much to see in town, but the riverside fishing harbor is always chock-a-block with brightly-painted boats and there are sights nearby including the Ke Ga lighthouse and Ta Cu Mountain.

Lao Cai is squeezed right next to the Vietnam–China border. Razed in the Chinese invasion of 1979, most of the buildings here are modern. The border crossing slammed shut during the 1979 war and only reopened in 1993. Now it’s a bustling spot fuelled by growing cross-border trade.

Most of the bases and bunkers have long vanished, but this 5km strip of land on either side of the Ben Hai River is still known by its American War moniker: the DMZ. From 1954 to 1975 it acted as a buffer between the North and the South. Ironically, the DMZ became one of the most militarised areas in the world, forming what Time magazine called ‘a running sore’.

Few parts of Vietnam stir the imagination with the lure of adventure quite like the highlands. The ribbon that is the Ho Chi Minh Hwy winds its scenic way past coffee plantations, pine-studded mountains, rice paddies with their wallowing buffalo, enormous reed-covered lakes and peaceful villages, laying down the challenge of a two-wheeled journey.

The geographic heart of the nation, central Vietnam is packed with historic sights and cultural interest, and blessed with ravishing beaches and outstanding national parks. Marvel at Hue and its Imperial Citadel, royal tombs and excellent street food. Savour the unique heritage grace of riverside jewel Hoi An, and tour the military sites of the Demilitarised Zone (DMZ). Check out Danang, fast emerging as one of the nation’s most dynamic cities. Also emerging as a must-visit destination is the extraordinary Phong Nha region, home to three gargantuan cave systems (including the world’s largest cave), and a fascinating war history concealed amid stunning scenery. Enjoy well-earned downtime on the golden sands of An Bang Beach or learn to cook central Vietnamese cuisine, the nation’s most complex. With improving highways, and upgraded international airports at Hue and Danang, access to this compelling and diverse part of Vietnam has never been easier.

South of Hanoi, Ninh Binh province is blessed with natural beauty, cultural sights and the Cuc Phuong National Park. Highlights include boat trips amid karst landscapes at Tam Coc and the Unesco World Heritage-listed Trang An Grottoes.