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South of Hanoi, Ninh Binh province is blessed with natural beauty, cultural sights and the Cuc Phuong National Park. Highlights include boat trips amid karst landscapes at Tam Coc and the Unesco World Heritage-listed Trang An Grottoes.

Northwest Vietnam, with its rocky, cone-like mountains, high vistas and deep valleys, encompasses some of the most extreme geography in the country – if not all of Southeast Asia. Travelling to the more remote parts of the region takes time and effort, but those short on either can stick around Sapa, the surrounding hills of which are a microcosm of the region as a whole.

Dong Van is the Ha Giang region's most popular overnight stop and, not coincidentally, is home to some solid accommodation and food. But the real reason to come is for the Sunday market, one of the region's biggest and most colourful. The town is also a good base for day treks around nearby minority villages and nearby sights such as the Lung Cu flag tower and the Lung Cam Cultural Tourist Village.

The geographic heart of the nation, central Vietnam is packed with historic sights and cultural interest, and blessed with ravishing beaches and outstanding national parks. Marvel at Hue and its Imperial Citadel, royal tombs and excellent street food. Savour the unique heritage grace of riverside jewel Hoi An, and tour the military sites of the Demilitarised Zone (DMZ). Check out Danang, fast emerging as one of the nation’s most dynamic cities. Also emerging as a must-visit destination is the extraordinary Phong Nha region, home to three gargantuan cave systems (including the world’s largest cave), and a fascinating war history concealed amid stunning scenery. Enjoy well-earned downtime on the golden sands of An Bang Beach or learn to cook central Vietnamese cuisine, the nation’s most complex. With improving highways, and upgraded international airports at Hue and Danang, access to this compelling and diverse part of Vietnam has never been easier.

Fringed with white-sand beaches and with large tracts still cloaked in dense tropical jungle, Phu Quoc rapidly morphed from a sleepy island backwater to a must-visit beach escape for Western expats and sun-seeking tourists. Beyond the resorts lining Long Beach, rapid development beginning on the east coast and mega resorts in sight of Sao Beach, there's still ample room for exploration and escaping the sometimes littered waters. Dive the reefs, kayak in the bays, eat up the back-road kilometres on a motorbike or just lounge on the beach, followed by a massage and a fresh seafood dinner.

Steadily being transformed into a vast new city, Tuy Hoa is characterised by its vast plaza and multi-laned boulevards. It’s a possible overnight stop to break up a longer journey, especially for cyclists brave enough to tackle Hwy 1, but most visitors are just passing through.

Ha Tien may be part of the Mekong Delta, but lying on the Gulf of Thailand it feels a world away from the rice fields and rivers that typify the region. There are dramatic limestone formations peppering the area, which are home to a network of caves, some of which have been turned into temples. Plantations of pepper trees cling to the hillsides. On a clear day, Phu Quoc Island is easily visible to the west.

Ninh Binh is a good base for exploring quintessentially Vietnamese limestone scenery. Few Western tourists head here, but many Vietnamese flock to nearby sights, including the nation’s biggest pagoda and the Unesco World Heritage–listed Trang An grottoes.

Cat Tien comprises an amazingly biodiverse area of lowland tropical rainforest. The 72,000-hectare park is one of the outstanding natural treasures in Vietnam, a true jungle, and the hiking, mountain biking and birdwatching here are the best in the south of the country. At weekends and public holidays it gets busy with domestic tourists – it's worth calling ahead to book the most popular excursions.

Once upon a time, Mui Ne was an isolated stretch of shoreline where pioneering travellers camped on the sand. Times have changed and it's now a string of beach resorts, which have fused into one long coastal strip. These resorts are, for the most part, mercifully low-rise and set amid pretty gardens by the sea. The original fishing village is still here, but tourists outnumber locals these days. There are a handful of luxury hotels (and a smattering of cheap guesthouses) but Mui Ne is mainly a midrange resort.