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Once upon a time, Mui Ne was an isolated stretch of shoreline where pioneering travellers camped on the sand. Times have changed and it's now a string of beach resorts, which have fused into one long coastal strip. These resorts are, for the most part, mercifully low-rise and set amid pretty gardens by the sea. The original fishing village is still here, but tourists outnumber locals these days. There are a handful of luxury hotels (and a smattering of cheap guesthouses) but Mui Ne is mainly a midrange resort.

Ninh Binh is a good base for exploring quintessentially Vietnamese limestone scenery. Few Western tourists head here, but many Vietnamese flock to nearby sights, including the nation’s biggest pagoda and the Unesco World Heritage–listed Trang An grottoes.

The epicentre of the Mekong Delta, Can Tho is the largest city in the region and feels like a metropolis after a few days exploring the backwaters. As the political, economic, cultural and transportation centre of the Mekong Delta, it’s a buzzing town with a lively waterfront lined with sculpted gardens, an appealing blend of narrow backstreets and wide boulevards, and perhaps the greatest concentration of foreigners in the delta. It is also the perfect base for nearby floating markets, the major draw for tourists who come here to boat along the many canals and rivers leading out of town.

Ho Chi Minh City (HCMC) is Vietnam at its most dizzying: a high-octane city of commerce and culture that has driven the country forward with its pulsating energy. A chaotic whirl, the city breathes life and vitality into all who settle here, and visitors cannot help but be hauled along for the ride.

A popular weekend escape from HCMC, Vung Tau rocks at weekends when beach-starved locals and expats descend in numbers, but it is relatively quiet during the week. The city enjoys a spectacular location on a peninsula, with ocean on three sides; the light and sea air make it a refreshing break from sultry Saigon.

Tra Vinh, one of the prettiest towns in the Mekong Delta, is a peaceful place to explore the region's little-touted Cambodian connection. Around 300,000 ethnic Khmer live in the surrounding province and the area is dotted with more than 140 Khmer pagodas. With wide boulevards shaded by lines of trees, the town itself is more symbolic of the French colonialist era, but get beyond the outskirts and you'll soon discover that Khmer culture is still alive and well in these parts of Vietnam. Tra Vinh also has a small but active Chinese community, one of the few such communities that remain in the Mekong Delta region.

The bustling port city of Phan Thiet is traditionally known for its nuoc mam (fish sauce), producing millions of liters of the stuff per annum. There's not much to see in town, but the riverside fishing harbor is always chock-a-block with brightly-painted boats and there are sights nearby including the Ke Ga lighthouse and Ta Cu Mountain.

With 307 species of bird, 133 species of mammal, 122 species of reptile and more than 2000 species of plant, Cuc Phuong National Park is one Vietnam’s most important protected areas.

Beyond the urban buzz and excitement of Ho Chi Minh City, the attractions of the surrounding region include fascinating cultural and historical sights such as the Cu Chi tunnels and the Cao Dai Holy See temple at Tay Ninh. Also worth exploring is the Unesco-accredited area around Can Gio, especially the extensive mangrove forests that were an integral part of the Viet Cong resistance effort during the American War.

Dalat is an alternative Vietnam: the weather is spring-like instead of tropical hot, the town is dotted with French-colonial villas rather than socialist architecture, and the surrounding farms cultivate strawberries, coffee and flowers instead of rice.