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Isolated from the mainland, the Con Dao islands are one of Vietnam's star attractions. Long the preserve of political prisoners and undesirables, they now turn heads thanks to their striking natural beauty. Con Son, the largest of this chain of 15 islands and islets, is ringed with lovely beaches, coral reefs and scenic bays, and remains partially covered in tropical forests. In addition to hiking, diving and exploring deserted coastal roads there are excellent wildlife-watching opportunities, such as the black giant squirrel and endemic bow-fingered gecko.

Ha Tien may be part of the Mekong Delta, but lying on the Gulf of Thailand it feels a world away from the rice fields and rivers that typify the region. There are dramatic limestone formations peppering the area, which are home to a network of caves, some of which have been turned into temples. Plantations of pepper trees cling to the hillsides. On a clear day, Phu Quoc Island is easily visible to the west.

Ho Chi Minh City (HCMC) is Vietnam at its most dizzying: a high-octane city of commerce and culture that has driven the country forward with its pulsating energy. A chaotic whirl, the city breathes life and vitality into all who settle here, and visitors cannot help but be hauled along for the ride.

Often referred to as the Ba Be Lakes, Ba Be National Park was established as a national park in 1992. The scenery here swoops from limestone mountains peaking at 1554m down into plunging valleys wrapped in dense evergreen forests, speckled with waterfalls and caves, with the lakes themselves dominating the very heart of the park.

Practically obliterated during the American War, Vinh was rebuilt with East German aid – hence the brutalist concrete architecture dominating downtown. The only reasons to stop here are if you're a Ho Chi Minh devotee (he was born in a nearby village), or if you're heading to Laos.

Highlights of the Danang region include the city's impressive urban energy, the rapidly evolving beach scene to the east of the river, and more remote and spectacular coastal scenery of the nearby Son Tra Peninsula. Look forward to some of Vietnam's best seafood and street food. It's worth booking a walking tour with a local to best understand Danang.

Beyond the urban buzz and excitement of Ho Chi Minh City, the attractions of the surrounding region include fascinating cultural and historical sights such as the Cu Chi tunnels and the Cao Dai Holy See temple at Tay Ninh. Also worth exploring is the Unesco-accredited area around Can Gio, especially the extensive mangrove forests that were an integral part of the Viet Cong resistance effort during the American War.

Designated a Unesco World Heritage Site in 2003, the remarkable Phong Nha-Ke Bang National Park contains the oldest karst mountains in Asia, formed approximately 400 million years ago. Riddled with hundreds of cave systems – many of extraordinary scale and length – and spectacular underground rivers, Phong Nha is a speleologists’ heaven on earth.

The site of Vietnam’s most extensive Cham remains, My Son enjoys an enchanting setting in a lush jungle valley, overlooked by Cat’s Tooth Mountain (Hon Quap). The temples are in poor shape – only about 20 structures survive where at least 68 once stood – but the intimate nature of the site, surrounded by gurgling streams, is still enthralling.

Quang Ngai city is something of an overgrown village, so most visitors only drop by for a spot of grazing at lunchtime. The few travelers who venture here for longer usually do so to pay their respects to the victims of the most famous atrocity of the American War at nearby Son My.