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With 307 species of bird, 133 species of mammal, 122 species of reptile and more than 2000 species of plant, Cuc Phuong National Park is one Vietnam’s most important protected areas.

This really is a tale of two cities: Phan Rang hugging the shoulders of Hwy 1 and Thap Cham straddling Hwy 20 as it starts its long climb to Dalat. Anyone travelling Vietnam from north to south will notice a big change in the vegetation when approaching the joint capitals of Ninh Thuan province. The familiar lush green rice paddies are replaced with sandy soil supporting only scrubby plants. Local flora includes poinciana trees and prickly-pear cacti with vicious needles.

Meo Vac is a small but charming district capital hemmed in by steep karst mountains and, like many towns in the northwest, it is steadily being settled by Vietnamese from elsewhere. The journey here along the spectacular Mai Pi Leng Pass, which winds for 22km from Dong Van, is the main attraction. The road has been cut into the side of a cliff with a view of rippling hills tumbling down to the distant waters of the Nho Que River far below. Right at the top of the pass is a lookout point where you can stop to take in the scenery.

The site of Vietnam’s most extensive Cham remains, My Son enjoys an enchanting setting in a lush jungle valley, overlooked by Cat’s Tooth Mountain (Hon Quap). The temples are in poor shape – only about 20 structures survive where at least 68 once stood – but the intimate nature of the site, surrounded by gurgling streams, is still enthralling.

Wow, the vistas. This is Vietnam's big-sky country; a place of rippling mountains, cascading rice terraces and the winnowed-out karst topography for which the region is famed.

South of Hanoi, Ninh Binh province is blessed with natural beauty, cultural sights and the Cuc Phuong National Park. Highlights include boat trips amid karst landscapes at Tam Coc and the Unesco World Heritage-listed Trang An Grottoes.

Draped along the banks of the Hau Giang River (Bassac River), Chau Doc sees plenty of travelers washing through on the river route between Cambodia and Vietnam. A likeable little town with significant Chinese, Cham and Khmer communities, Chau Doc's cultural diversity – apparent in the mosques, temples, churches and nearby pilgrimage sites – makes it fascinating to explore even if you're not Cambodia-bound. Taking a boat trip to the Cham communities across the river or heading to nearby Sam Mountain and Tra Su Bird Sanctuary are other highlights, while the bustling market and intriguing waterfront provide fine backdrops to a few days of relaxation.

Few parts of Vietnam stir the imagination with the lure of adventure quite like the highlands. The ribbon that is the Ho Chi Minh Hwy winds its scenic way past coffee plantations, pine-studded mountains, rice paddies with their wallowing buffalo, enormous reed-covered lakes and peaceful villages, laying down the challenge of a two-wheeled journey.

The epicentre of the Mekong Delta, Can Tho is the largest city in the region and feels like a metropolis after a few days exploring the backwaters. As the political, economic, cultural and transportation centre of the Mekong Delta, it’s a buzzing town with a lively waterfront lined with sculpted gardens, an appealing blend of narrow backstreets and wide boulevards, and perhaps the greatest concentration of foreigners in the delta. It is also the perfect base for nearby floating markets, the major draw for tourists who come here to boat along the many canals and rivers leading out of town.

Beyond the urban buzz and excitement of Ho Chi Minh City, the attractions of the surrounding region include fascinating cultural and historical sights such as the Cu Chi tunnels and the Cao Dai Holy See temple at Tay Ninh. Also worth exploring is the Unesco-accredited area around Can Gio, especially the extensive mangrove forests that were an integral part of the Viet Cong resistance effort during the American War.