Situated on the eastern edge of the Tibetan Plateau, this lively and hugely diverse provincial capital makes a good base from which to dive into the surrounding sights and on to the more remote regions of Qinghai and beyond. Though many travellers use Xining (西宁, Xīníng) as a jumping-off or landing point from the Qinghai–Tibet Railway, it’s also a wonderful place to encounter the province’s varied cultures – Muslim (Hui, Salar and Uyghur), Tibetan and Han Chinese – especially the rich culinary mix that these groups bring together. There's superb food and a scattering of tempting cafes as well as an outstanding museum of Tibetan culture, some beautiful temples and mosques, plus the remains of the old city wall, so try not to race through without putting aside some time to explore.
The centre of the Tibetan Buddhist world for over a millennium, Lhasa (ལྷ་ས་; 拉萨; Lāsà; literally the 'Place of the Gods') remains largely a city of wonders. Your first view of the red-and-white Potala Palace soaring above the Holy City raises goosebumps and the charming whitewashed old Tibetan quarter continues to preserve the essence of traditional Tibetan life. It is here in the Jokhang, an otherworldly mix of flickering butter lamps, wafting incense and prostrating pilgrims, and the encircling Barkhor pilgrim circuit, that most visitors first fall in love with Tibet.
The original city core and the sole part of Shanghai to pre-date the 1850s, the Old City (上海老城厢; Shànghăi Lăo Chéngxiāng) is a favourite with visitors hoping to glimpse ‘traditional’ China. Many of the older buildings have been replaced with modern apartment blocks, but there are still more temples here than in the rest of the city combined, and pockets are impregnated with atmosphere and shabby charm.
Shaanxi (陕西; Shǎnxī) is where it all began for China. As the heartland of the Qin dynasty (秦朝), whose warrior emperor united much of China for the first time, Shaanxi was the cradle of Chinese civilisation and the fountainhead of Han culture. Xi'an marked the beginning and end of the Silk Road and was a buzzing capital long before anyone knew of Beijing and its Forbidden City.
Chengdu (成都, Chéngdū) is no great draw when it comes to major tourist sites, yet this is one of the few super-sized Chinese cities that most visitors do end up enjoying. There's a relaxing teahouse culture – favorite local institutions have been serving the same brews for generations; a lively nightlife that mixes craft beer bars and super-hip clubs with Sichuan opera shows; and delicious food that is famous for its heat, history and variety even in cuisine-rich China, and is very much a point of pride: Chengdu is, after all, Unesco's first-ever City of Gastronomy. Oh, and as if that's not enough, this is the place to come to see China's cutest residents – the giant pandas.
The fertile Dunhuang (敦煌, Dūnhuáng) oasis has for millennia been a refuge for weary Silk Road travelers. Most visitors stayed long enough only to swap a camel; but some stayed, building the forts, towers and cave temples that are scattered over the surrounding area. These sites, along with some dwarfing sand dunes and desertscapes, make Dunhuang a magnificent place to visit.
Home to the wondrous Harbin Ice & Snow Festival, and the world's largest indoor ski facility, the capital of Heilongjiang (哈尔滨; Hā’ěrbīn), located on the Songhua River, is a stylish city and a highlight of any trip through Dongbei.
Lamma, Hong Kong's laid-back "hippie island," is easily recognizable at a distance by the three coal chimneys crowning its hilly skyline. The chimneys stand out so much because Lamma, home to 6000 or so, is otherwise devoid of high-rise development. Here it's all about lush forests, hidden beaches and chilled-out villages connected by pedestrian paths. You won't see any cars here, but be prepared for spotting the odd snake.
Vast, thinly populated and with an average altitude of over 14,764 ft (4500m), western Tibet (Ngari, མངའ་རིས་) is a rough and ready frontier occupying one of the remotest corners of Asia. For most travelers the main attractions of what is likely to be a two- or three-week overland trip are the almost legendary destinations of Mt Kailash and Lake Manasarovar. Indeed, many of the Tibetan and Indian pilgrims you meet on this road have been planning a visit all their lives.
The remote highways running along the north of Kham can be used to exit the Tibet Autonomous Region into Qinghai, Sichuan, or as part of a long loop around Kham. At the time of writing only one route into Qinghai was open to foreign travellers: Hwy 109 (also known as the Qinghai–Tibet Hwy) running from Lhasa to Xining. As the railway covers the same route most people do not hire private vehicles for this section. A few hardy souls make the trip by bike, crossing into Tibet over the 5180m Tangu-la pass. Under current regulations, a guide still needs to accompany you and your bicycle in a support vehicle. Check out Bike China for more.