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This stretch of bushveld between Pretoria and the Kalahari is famous for Sun City, the southern hemisphere’s answer to Las Vegas. Though its slot machines and kitsch edifices are grotesquely fascinating, it's the nearby parks and reserves that we really love – Madikwe Game Reserve is a real gem, while Pilanesberg has terrific wildlife and is very accessible. And for that once-in-a-lifetime, romantic Out of Africa–style experience, a night in the bush at Madikwe’s exclusive lodges can’t be beaten.

Embracing an exquisitely beautiful lagoon and surrounded by ancient forests, Knysna (pronounced ny-znah) is probably the most famous town on the Garden Route. Formerly the centre of the timber industry, supplying yellowwood and stinkwood for railway lines, shipping and house-building, it still has several shops specialising in woodwork and traditional furniture. The lagoon is popular with sailing enthusiasts, and there are plenty of boat trips on offer.

This shipwreck-strewn coastline rivals any in the country in terms of beauty and wilderness, stretching over 350km from just east of East London to Port Edward. Often referred to as the ‘Transkei’ (the name of the apartheid-era homeland that once covered most of this area), the Wild Coast region also stretches inland, covering pastoral landscapes where clusters of rondavels (round huts with a conical roofs) scatter the rolling hills covered in short grass.

The iSimangaliso Wetland Park, a Unesco World Heritage site, stretches for 220 glorious kilometres from the Mozambique border to Maphelane, at the southern end of Lake St Lucia. With the Indian Ocean on one side and a series of lakes (including Lake St Lucia) on the other, the 2038-sq-mile (3280-sq-km) park protects five distinct ecosystems, offering everything from offshore reefs and beaches to lakes, wetlands, woodlands and coastal forests. Loggerhead and leatherback turtles nest along the park’s shores; whales and dolphins appear offshore and the park is occupied by numerous animals, including antelopes, hippos and zebras. The ocean beaches pull big crowds during the holiday season for everything from diving to fishing.

Venturing inland and upwards from Cape Town you’ll find the Boland, meaning ‘upland’. It’s a superb wine-producing area, and indeed the best known in South Africa. The magnificent mountain ranges around Stellenbosch and Franschhoek provide ideal microclimates for the vines.

Hermanus is generally considered the best land-based whale-watching destination in the world. From June to December, the bay becomes the swimming grounds for a large number of southern right whales. So what might have otherwise just been a small fishing village is today a large, bustling town with an excellent range of accommodation, restaurants and shops.

Gauteng (pronounced how-teng) may be a small province but it also is the economic heart of the nation. Its epicentre is Johannesburg (Jo'burg or Jozi), the country's largest city. And what a city! Jo'burg's old downtown area is undergoing an astonishing rebirth. Once considered a place to avoid, Jo'burg is now one of the most inspiring and happening metropolises in the world.

The Sunshine Coast has everything the country is known for – pristine beaches, wildlife, stunning scenery, great outdoor activities and culture. It covers a significant chunk of the Eastern Cape coastline, including Port Elizabeth, the seaside towns of Jeffrey's Bay and Port Alfred, and numerous sandy beaches. In the hinterland are the best wildlife-watching areas within easy reach of the coastline between Cape Town and Durban: Addo Elephant National Park and the nearby private reserves.

Plettenberg Bay, or ‘Plett’ as it’s more commonly known, is a resort town through and through, with mountains, white sand and crystal-blue water making it one of the country’s top local tourist spots. As a result, things can get very busy, but the town retains a relaxed, friendly atmosphere and does have excellent hostels. The scenery to the east in particular is superb, with some of the best coast and indigenous forest in South Africa.